Board of Intermediate and Secondary Education Multan was established on 30th March1968.Its establishment came into being after an ordinance of Government of West Pakistan, which was passed by the Assembly of Pakistan on 24, May during a meeting In the beginning, Camp Office of Multan board started working in the Government Central Training College Lahore, on the mid June, it was shifted to Multan headquarter. In the beginning Quetta, Kallat, Bahawalpur and Multan  including Dera Ghazi Khan was included in the Multan Board. In 1968, Quetta and kallat started working separately, in1978 Bahawal Pur Board was established and started working separately. In 1982, Dera Ghazi Khan Board was separated from Multan Board. Now Board Of Intermediate And Secondary Education is working in every division